Clinical practice guidelines

Evidence-based clinical guidance for myeloma diagnosis and management. Expert-authored resources to support health professionals in patient care.

This resource hub provides clinicians with practical, evidence-based guidance for the diagnosis and management of myeloma and related conditions.

From clinical practice guidelines to position statements, the Medical and Scientific Advisory Group (MSAG) author these documents to support health professionals in delivering patient care.

MSAG clinical practice guidelines

Clinical practice guideline Newly Diagnosed Transplant Ineligible Guidelines March 2026 on behalf of MSAG Medical Scientific Advisory Group (MSAG) to Myeloma Australia (MA)

Newly diagnosed transplant ineligible guidelines

A clinical guideline outlining recommended treatments for patients newly diagnosed with multiple myeloma who are not eligible for stem cell transplantation.

Clinical practice guideline Treatment of patients with relapsed refractory multiple myeloma. Hang Quach on behalf of MSAG
Medical Scientific Advisory Group (MSAG) to Myeloma Australia (MA) 2026

Treatment of patients with relapsed refractory multiple myeloma

An Australia‑specific, evidence‑based guideline for personalised treatment of relapsed or refractory multiple myeloma, prioritising early use of effective therapies within PBS access limits.

CLINICAL PRACTICE GUIDELINE
Management of patients with newly diagnosed multiple myeloma who are eligible for autologous stem cell transplantation
Georgia McCaughan, Simon Harrison and Hang Quach on behalf of MSAG
MEDICAL SCIENTIFIC ADVISORY GROUP (MAG) TO MYELOMA AUSTRALIA (MA)
2026

Newly diagnosed transplant eligible guideline

An Australian guideline for treating newly diagnosed, transplant‑eligible multiple myeloma, centred on induction therapy, autologous stem cell transplantation, and maintenance.

Selinexor

A practical resource for Australian clinicians to optimize the use of selinexor, focusing on maximizing efficacy while minimizing and managing predictable toxicities through proactive supportive care and patient engagement.

MSAG systemic al amyloidosis guidelines front cover

Systemic AL Amyloidosis guidelines

An Australian guideline outlining diagnosis, staging, treatment and supportive care for systemic AL amyloidosis.

Optimal care pathway for people with multiple myeloma cover

Optimal care pathway for people with multiple myeloma

A guideline for clinicians to manage each step of the care pathway from diagnosis to treatment, supportive care and disease progression.

Front cover the MSAG imaging guidelines cover

Imaging guidelines

Evidence-based guidelines on the use of imaging for the diagnosis, assessment and management of myeloma and associated plasma cell disorders.

MSAG prevention of Infection in myeloma

Prevention of infection in myeloma

An evidence‑based Australian guideline outlining infection risk assessment, screening, prophylaxis and vaccination strategies for patients with multiple myeloma.

MSAG VRd Cover

VRd

Guidelines for using bortezomib, lenalidomide, and dexamethasone (VRd) as first-line treatment for multiple myeloma, emphasising its avaliability in Australia, efficacy, and the need to tailor regimens based on patient fitness and toxicity risk.

waldenstrom 2022 cover update

Waldenström Macroglobulinaemia (2022)

An Australian consensus guideline for the diagnosis and treatment of Waldenström macroglobulinaemia, covering frontline and relapsed therapies within current PBS access.

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